System Overview

This section provides an overview of the NovaSeq X Plus system, including information on hardware, software, data analysis, and run management. For detailed specifications, data sheets, applications, and related products, refer to the NovaSeq X Series support site page.

Features

High throughput and accuracy
Delivers meaningful genomic insights at scale using high throughput next-generation sequencing (NGS).
Uses XLEAP-SBS chemistry, an update to Illumina SBS chemistry.
Enables comprehensive and efficient analysis of NGS data using data analysis pipelines powered by the Illumina DRAGEN Bio-IT Platform.
Productivity
Allows multiple flow cell configurations to enable ~165 Gb to 16 Tb of sequencing data and up to 104 billion paired-end reads per run. Output is adjustable to match sequencing workflow needs.
Provides integrated onboard and cloud-based data analysis workflows and lossless data compression powered by the Illumina DRAGEN Bio-IT Platform.
Sustainability
Ships at ambient temperatures (no ice packs or dry ice) by using lyophilized reagents, which reduces cartridge volume, packaging weight, and the amount of shipping materials used.
Reduces the plastic mass of the instrument by providing recyclable plastics and buffer cartridges made with plant-based biopolymers.