Polygenic Risk Score Software

The Polygenic Risk Score (PRS) software - Predict module provides PRS predictions from IDAT files produced by the iScan System™. The analysis includes PRS predictions and imputed genotype results, and the production of quality metrics. Analysis can be started using the Microarray Analysis Setup in BaseSpace™ Sequence Hub.

The Predict module runs using Illumina Connected Analytics (ICA), a hosted environment for managing, processing, and analyzing genomic data. Before sending data to ICA, BeadChip DMAP files must be accessioned with the ICA command-line interface (CLI). To download and install ICA CLI v1.2, refer to the instructions in the ICA online help.