NextSeq 550Dx Research Mode Considerations

Instructions in this guide, with some exceptions, are applicable to the NextSeq 550Dx instrument when in research mode with NCS v4.0 or later. When in research mode with NCS v3.0, refer to the NextSeq 550Dx Research Mode Instrument Reference Guide (document # 1000000041922).

Your source for general Local Run Manager software instructions depends on the mode in use on the NextSeq 550Dx instrument. When in research mode, see the Local Run Manager v4 Software Guide (document # 200036672). When in diagnostic mode, see the Local Run Manager software instructions in NextSeq 550Dx Instrument Reference Guide (document # 1000000009513). Local Run Manager software is not available for NCS v3.0.

The differences between the NextSeq 550Dx in research mode and the NextSeq 550 include the following.

•

Consumables compatibility.

•

Starting the instrument.

•

Instrument reboot and shutdown.