System Overview
The
Features
| • | Scalable sequencing—The NovaSeq 6000Dx scales up to production-level sequencing with high-quality data for a broad range of applications. |
| • | Patterned flow cell—A patterned flow cell generates tightly spaced clusters for high cluster density and data output. |
| • | Onboard ExAmp mixing—The NovaSeq 6000Dx mixes the ExAmp reagents with the library, amplifies the library, and performs cluster generation for a streamlined sequencing workflow. |
| • | High-throughput line scanning—The NovaSeq 6000Dx uses one camera with bidirectional scanning technology to quickly image the flow cell in two color channels simultaneously. |
| • | Dual mode—The NovaSeq 6000Dx includes a single boot hard drive with separate in vitro diagnostic (IVD) and research use only (RUO) modes. The mode is selected using the toggle on the Sequencing, Runs, and Applications screens. After it is selected, the mode is clearly labeled on all screens. |
| • | Illumina DRAGEN Server for NovaSeq 6000Dx—The included DRAGEN Server provides hardware accelerated data analysis. |
| • | Illumina Run Manager—Plan runs, manage users, and set up analysis applications both on the NovaSeq 6000Dx and off instrument through a web browser using Illumina Run Manager. |
Dual Mode Considerations
In vitro diagnostic (IVD) sequencing assays are executed in IVD mode. Only IVD sequencing reagents can be used in IVD mode. Always make sure that the correct mode is selected before beginning run planning.
This resource describes the use of the NovaSeq 6000Dx Instrument in IVD mode unless otherwise noted. Refer to the NovaSeq 6000 Sequencing System Guide (document # 1000000019358) for information on RUO features, including BaseSpace Sequence Hub integration.
Safety Considerations
Review Safety & Compliance before performing any procedures on the system.
