Environmental Considerations

Instrument Environmental Specifications

Element

Specification

Temperature*

Maintain a lab temperature of 15°C to 30°C. During a run, do not allow the ambient temperature to vary more than ±2°C. Failure to operate the instrument within the temperature range can degrade performance or cause a run to fail.

Humidity*

Maintain a noncondensing relative humidity between 20–65%.

Elevation

Locate the instrument at an elevation below 2000 m (6500 ft).

Air Quality

Operate the instrument in an indoor environment with air particulate cleanliness levels per ISO 9 (ordinary room air), or better.

Keep the instrument away from sources of dust.

Vibration

Limit the continuous vibration of the lab floor to ISO operating room level (baseline), or better.

During a sequencing run, limit intermittent disturbances or shocks to the floor near the instrument. Do not exceed ISO operating room level.

Lab Exhaust

Ventilation should be appropriate for handling of hazardous materials in reagents and in accordance with applicable regional, national, and local laws and regulations. For additional environmental, health, and safety information, refer to the SDS at support.illumina.com/sds.html.

*Avoid a combination of high temperature and high humidity. For example, 30°C and 65% relative humidity.

Noise Output

Noise Output

Distance From Instrument

< 75 dB

1 m (3.3 ft)
Heat Output

Power Consumption

Thermal Output

Maximum: 2700 Watts

Average: 2200 Watts

Maximum: 9200 BTU/h*

Average: 7507 BTU/h

*Excludes thermal output from UPS.

A 25.4 cm (10 in), round, vertical chimney vents 80% of instrument heat output. You can vent to the room or connect the chimney to a user-supplied duct.

Use the following guidelines for venting ducts.

• Flexible ducting is preferred.
• Avoid bending flexible ducts where possible. Keep bends in flexible ducts to a minimum.
• Flexible ducts with bends must maintain the 25.4 cm (10 in) diameter of the chimney at all points.
• Remove kinks or other restrictions to the airflow.
• Rigid ducting can be used. Use of rigid ducting can require Illumina personnel to move the instrument for service.
• Use the shortest length of ducting possible.
• Route to a space with sufficient ventilation to prevent airflow restriction or backup into the instrument.

Failure to follow these guidelines can impact instrument performance and can cause run failures.

Chimney airflow is up to 450 CFM. Chimney air temperature is up to 12°C higher than ambient temperature.

Chimney Placement for Venting

The NovaSeq X and NovaSeq X Plus Sequencing Systems are equipped to dispense used reagent buffer to a customer-supplied bulk container for separate processing or handling. The supplied external used reagent tubes included in the accessory kit are 5 meters long, and connect to the left rear of the instrument.

Illumina only supports external used reagent collection with the supplied tubes. Each tube contains the buffer waste from a single flow cell position, and must be routed individually to the bulk container.

The container must be placed within 5 meters of the instrument. The aperture must be at a height of 1000 mm or less from the floor.