Prepare for Protocol

This preparation is required to perform the protocol steps leading up to the overnight hybridization step. Illumina recommends that you gather and thaw reagents at the beginning of the day.

1. Remove the reagents from the box and thaw as follows.
Room Temperature Storage

Reagent

Box Name

Instructions

MB Prep Buffer (M-P)

Illumina Protein Prep (IPP), Proteomics Assay, All Assays 22°C Box

Use at room temperature.

2°C to 8°C Storage

Reagent

Box Name

Instructions

Assay Buffer (AB)

Not applicable

Can be used cold.

Elution Buffer (2-E)

Illumina Protein Prep (IPP), Proteomics Assay, All Assays 4°C Box

Bring to room temperature.

Magnetic Beads (M-B)

Illumina Protein Prep (IPP), Proteomics Assay, All Assays 4°C Box

Bring to room temperature.

MB Block (2-B)

Illumina Protein Prep (IPP), Proteomics Assay, All Assays 4°C Box

Bring to room temperature.

MB Wash Buffer, 20% (2-W)

Illumina Protein Prep (IPP), Proteomics Assay, All Assays 4°C Box

Bring to room temperature.

Photo Cleavage Buffer (1-PC)

Illumina Protein Prep (IPP), Proteomics Assay, All Assays 4°C Box

Bring to room temperature.

Quench Buffer (1-Q)

Illumina Protein Prep (IPP), Proteomics Assay, All Assays 4°C Box

Bring to room temperature.

Tag Diluent (1-D)

Illumina Protein Prep (IPP), Proteomics Assay, All Assays 4°C Box

Bring to room temperature.

-30°C to -10°C Storage

Reagent

Box Name

Instructions

100x Tag Reagent (1-T)

Illumina Protein Prep (IPP), Proteomics Assay, Plasma/Serum -20°C Box

Bring to room temperature.

Proteomics Probe Plate (PPP2)

Illumina Protein Prep (IPP), NGS, Box 3

Bring to room temperature.

SOMAmer-Bead Plate 11k (Dilution 1)

Illumina Protein Prep (IPP), Proteomics Assay, Plasma/Serum -20°C Box

Bring to room temperature.

SOMAmer-Bead Plate 11k (Dilution 2)

Illumina Protein Prep (IPP), Proteomics Assay, Plasma/Serum -20°C Box

Bring to room temperature.

SOMAmer-Bead Plate 11k (Dilution 3)

Illumina Protein Prep (IPP), Proteomics Assay, Plasma/Serum -20°C Box

Bring to room temperature.

-90°C to -70°C Storage

Reagent

Box Name

Instructions

Plasma/Serum Diluent

Illumina Protein Prep (IPP), Proteomics Assay, Plasma/Serum -80°C Box

Thaw in a room temperature water bath (minimum 20 minutes).

Make sure that the lid remains above water. Dry off before use.

2. Save the following Hyb program on the pre-PCR thermal cycler:
Choose the preheat lid option and set to 100°C
Set the reaction volume to 100 µl
95°C for 10 minutes
Decrease by 0.1°C per second until reaching 50°C
50°C for 1 hour
Decrease by 0.1°C per second until reaching 45°C
45°C for 2 hours
Decrease by 0.1°C per second until reaching 40°C
40°C for 4 hours
Decrease by 0.1°C per second until reaching 37°C
37°C for 8 hours
Hold at 37°C