Block List
The block list represents high noise regions in the panel where false positive variant calls are likely produced. As a result, all positions in the gVCF are marked as Filter=excluded_regions to indicate variant call results are not reliable in such regions.
The block list includes the following genes:
| • | HLA-A |
| • | HLA-B |
| • | HLA-C |
| • | KMT2B |
| • | KMT2C |
| • | KMT2D |
| • | chrY |
| • | Any position with VAF > 1% occurrence in six or more of the 60 baseline samples. |
