Overview
The Illumina® DRAGEN™ TruSight™ Oncology 500 Analysis Software
• | Single nucleotide variants (SNVs) |
• | Insertions |
• | Deletions |
• | Copy number variants (CNVs) |
• | Exon-level CNVs |
• | Multinucleotide variants (MNVs) |
TruSight Oncology 500 also detects immunotherapy biomarkers for tumor mutational burden (TMB) and microsatellite instability (MSI) in DNA. DNA library analysis outputs include TMB, variant call files for small and complex variants, MSI, and gene amplifications.
Details of the regions covered can be found in the assay manifest file. Contact your local Illumina representative for more information.
The DRAGEN TruSight Oncology 500 Analysis Software v2.1.1 allows for analysis on a single DRAGEN server or split across multiple servers.
TruSight Oncology 500 HRD is not available in all countries. For more information, refer to the TruSight Oncology 500 product page on the Illumina website or contact Illumina Technical Support.

The DRAGEN TruSight Oncology 500 Analysis Software v2.1.1 support pages on the Illumina support site provide information on compatibility with Illumina sequencing systems.
Use