ATAC Pipeline
The DRAGEN Single-Cell ATAC (scATAC) Pipeline can process single-cell ATAC-seq data sets from reads to a cell-by-peak read count matrix. The pipeline includes the following functions:
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Cell-barcode error correction for the barcode read |
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Chromatin accessibility peak calling |
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Fragment counting per cell and peak to measure chromatin accessibility |
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Sparse matrix output and QC metrics |
The functionality and options related to alignment and gene annotation are identical to DNA pipelines. For information, see DRAGEN DNA Pipeline.