Install and Uninstall

This section provides instructions for installing, verifying, and uninstalling DRAGEN for ILMN Cell-Free DNA Prep with Enrichment on a DRAGEN server.

Install and Perform System Check

1. Contact Illumina Customer Support to request a link to the installation script.
2. Download the installation package from the link provided by Illumina. The link expires after 7 days.
3. Wait for any in-progress analysis to complete.
4. Copy the install script to the /staging directory.
5. Use the following command to update the run script permissions:

sudo chmod +x /staging/install_DRAGENForILMNCellFreeDNAPrepWithEnrichment-1.0.0.run

6. Use the following command to execute the installation script, which runs for approximately 10 minutes:

sudo TMPDIR=/staging /staging/install_DRAGENForILMNCellFreeDNAPrepWithEnrichment-1.0.0.run

The script installs compatible DRAGEN software and removes any previously installed versions.

7. Activate the software license. Refer to the Site Prep Guide for your version of DRAGEN.
8. After the software is installed, use the following command to initiate a system check:

/usr/local/bin/check_DRAGENForILMNCellFreeDNAPrepWithEnrichment-1.0.0.sh

The system check verifies that the required resources are in place and that the software can successfully run on a test data set. The self-test runs for approximately 30 minutes. If the self-test prints a failure message, contact Illumina Technical Support.

Uninstall

The installation package includes an uninstall script, which is located in /usr/local/bin.

Executing the uninstall script removes application-related scripts, resources, and the Docker image.

To uninstall the app, run the following command as a root user:

uninstall_DRAGENForILMNCellFreeDNAPrepWithEnrichment-1.0.0.sh