Internal Tandem Duplications Calling

You can use the --sv-somatic-ins-tandup-hotspot-regions-bed ${BEDFILE} option to specify ITD hotspot regions to increase sensitivity for calling ITDs in somatic variant analysis. By default, DRAGEN SV automatically selects a reference-specific hotspots BED file from /opt/edico/config/sv_somatic_ins_tandup_hotspot_*.bed. The file includes FLT3, ARHGEF7, and KMT2A. To disable this feature, enter --sv-enable-somatic-ins-tandup-hotspot-regions false.

Revision History

Document #200033181 v02

For Research Use Only. Not for use in diagnostic procedures (except as specifically noted).

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Illumina DRAGEN Bio-IT Platform v4.2

dragen_v42

200033181_02_dragen-bio-it-platform-v4-2-doc.pdf