Clear Hard Drive Space

If there is insufficient data storage space, a warning notification displays during pre-run checks. You can check the available space and the space consumed by runs or resources. Use the following steps to clear space by deleting completed runs and installed resources from an instrument run folder.

Use only the NovaSeq X Series Control Software to delete runs. Avoid deleting runs manually through the operating system. Deleting runs manually can negatively impact the control software. You cannot requeue a deleted run.

1. Select the instrument icon to open the global navigation menu.
2. Select Runs.
3. For the run you want to delete, select the ellipsis icon in the Action column.
4. Select one of the following options.
• Delete run data—Deletes the sequencing and analysis output folders, but does not remove the run from the Completed tab. You can view the run details, but cannot view the DRAGEN secondary analysis report.
• Delete run—Deletes the run data and removes the run from the Completed tab.
5. In the dialog box, confirm run deletion.
6. Repeat steps 3–5 for each run that you want to delete.

Use the following instructions to remove reference genomes or reference files. With NovaSeq X Series Control Software v1.4 and later, you can also remove resources in Illumina Software Update Manager (ISUM). Refer to Software Updates.

1. Select the instrument icon to open the global navigation menu.
2. Select Settings, and then select Resource files.
3. Select the Genomes tab or Reference files tab.
4. For the genome or reference file you want to remove, select the delete icon.
5. In the dialog box, select Yes, remove to confirm.
6. Repeat steps 4 and 5 for each genome or reference file that you want to remove.